Servex®

Aceclofenac Tablet

Servex® tablet: Each film  coated tablet contains Aceclofenac BP 100 mg.

Servex® (Aceclofenac) belongs to the group of NSAIDs.

Servex® (Aceclofenac) works by blocking the action of a substance in the body called Cyclo-oxygenase. Cyclo-oxygenase is involved in the production of various chemicals in the body, some of which are known as prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause pain, swelling and inflammation such as arthritic condition. Aceclofenac is used to relieve pain and inflammation in arthritic conditions.

Indication

Pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

Adult: Recommended dose is 100 mg twice daily.

Children: Not recommended.


Generally Aceclofenac is well tolerated. The majority of side effects observed have been reversible and of a minor nature and include gastrointestinal disorders (dyspepsia, abdominal pain, nausea and diarrhoea) and occasional occurance of dizziness. Dermatological side effects including pruritus and rash. Abnormal hepatic enzyme levels and raised serum creatinine have occasionally been reported.

The safety of this medicine for use during pregnancy and lactation has not been established. It is not recommended for use in pregnancy and lactation unless considered essential by doctor. 

Aceclofenac is contraindicated in patients previously sensitive to Aceclofenac or Aspirin or other NSAIDs.

There is no human data available on the consequences of Aceclofenac overdosage. After overdosage, following therapeutic measures are to be taken: absorption should be prevented as soon as possible by means of gastric lavage and treatment with activated charcoal. Supportive and symptomatic treatment should be given for complications.

Aceclofenac should be administered with caution to patients with symptoms moderate to severely decreased kidney function, gastrointestinal disorders, with a history of peptic ulceration, ulcerative colitis, crohn's disease, hepatic porphyria, and coagulation disorders. Patients suffering from severe hepatic impairment must be monitored. 

There may be an increased risk of bleeding from the gut if Aceclofenac is taken with anti-clotting medicines such as Warfarin.The effect of diuretics such as Frusemide (Furosemide) may be reduced by Aceclofenac.The use of Aceclofenac with Cyclosporin or ACE inhibitors may increase the risk of kidney problems and alterations to the potassium balance in the body. Aceclofenac should not be taken with any other NSAIDs, due to an increased risk of side effects. Convulsions may occur when Aceclofenac is given together with Quinolone antibiotics.

Store in a cool and dry place, keep away from light.

Servex® tablet: Box containing 5 Alu-Alu blister strips of 10 tablets each.