Anasec® capsule: Each capsule contains 20 mg of Omeprazole BP as enteric coated pellets.

Omeprazole is a specific inhibitor of the gastric proton pump (H+/K+ -ATPase) in the parietal cell. There it produces dose dependent inhibition of acid secretion by binding to the enzyme and effectively reduces gastric acid secretion. After oral administration the onset of the antisecretory effect of Omeprazole occurs within one hour, with the maximum effect occurring within two hours and inhibition of secretion lasts up to 72 hours. When the drug is discontinued, secretory activity returns gradually over 2 to 5 days.

Omeprazole, a racemic mixture of two active enantiomers, reduces gastric acid secretion through a highly targeted mechanism of action. It is a specific inhibitor of the acid pump in the parietal cell. It is rapid acting and provides control through reversible inhibition of gastric acid secretion with once daily dosing.


Omeprazole is a weak base and is concentrated and converted to the active form in the highly acidic environment of the intracellular canaliculi within the parietal cell, where it inhibits the enzyme H+/K+ -ATPase, the acid pump. This effect on the final step of the gastric acid formation process is dose dependent and provides for highly effective inhibition of both basal acid secretion and stimulated acid secretion, irrespective of the stimulus.

Omeprazole capsules are indicated for the treatment of: Reflux esophagitis, Duodenal ulcer, Gastric ulcer, NSAID-associated gastric and duodenal ulcers or erosions, Acid related dyspepsia, Zollinger-Ellison syndrome. In the treatment of peptic ulceration, the eradication of H. pylori, as the causative organism, must be a high priority. Accordingly, Omeprazole should be used as part of combination therapy for the eradication of H. pylori.

Maintenance- Omeprazole capsules are indicated for maintenance treatment of: Reflux esophagitis, Duodenal ulcer, Gastric ulcer and Zollinger-Ellison syndrome.

Esomeprazole, Delayed-Release Capsules should be swallowed whole and taken at least one hour before meal. Recommended adult dosage schedule:





Gastroesophageal Reflux Disease (GERD)

 Healing of Erosive  Esophagitis

20 mg or

40 mg

Once Daily for 4 to 8 Weeks*

Maintenance of Healing of Erosive Esophagitis

20 mg

Once Daily**

Symptomatic Gastro-esophageal Reflux Disease

20 mg

Once Daily for 4 Weeks***

Risk reduction of NSAIDs associated gastric ulcer

20 mg

Once daily for 4 weeks**

H. Pylori eradication to reduce the risk of the duodenal ulcer recurrence

Triple Therapy:




40 mg

1000 mg

500 mg

Once Daily for 10 Days

Twice Daily for 10 Days

Twice Daily for 10 Days

Paediatric use (12-17 years old) Short term treatment of GERD

20 mg or

40 mg

Once daily for up to 8 week

The majority of patients are healed within 4 to 8 weeks. For patients who do not heal after 4-8 weeks, an additional 4-8 weeks of treatment may be considered. **Controlled studies did not extend beyond six months. ***If symptoms do not resolve completely after 4 weeks, an additional 4 weeks of treatment may be considered.


No dosage adjustment is necessary. 

No dosage adjustment is necessary.

No dosage adjustment is necessary in patients with mild to moderate liver impairment. For patients with severe liver impairment, a dose of 20 mg of Esomeprazole should not be exceeded.

No dosage adjustment is necessary.

Safety and effectiveness in children have not been established.

More common side effects may include: Abdominal pain, diarrhea, headache, dermatitis ets. 

Use in Pregnancy & Lactation  

The effects of Esomeprazole during pregnancy have not been adequately studied. Those who are pregnant or plan to become pregnant should consult with the doctor. Because Esomeprazole is likely to appear in breast milk and could harm a nursing infant, so need to choose between taking Esomeprazole or breastfeeding your baby.

In case of overdose, seek medical attention immediately. Symptoms of overdose may include: Blurred vision, confusion, drowsiness, dry mouth, flushing, headache, nausea, rapid heartbeat and sweating etc.

Esomerpazole is contraindicated in patients with known hypersensitivity to Esomeprazole or to substituted Benzimidazoles. 

Before taking this medicine, tell your doctor if you have: 

          a compromised immune system 



This medicine may increase the risk of pneumonia in some patients. 

Esomeprazole is taken with certain other drugs; the effects either could be increased, decreased, or altered. Esomeprazole inhibits gastric acid secretion. Therefore, Esomeparzole may interfere with the absorption of drugs where gastric pH is the important determinant of bioavailability (e.g. Ketoconazole, Iron salts, and Digoxin). Co-administration of oral contraceptives, Diazepam, Phenytion, or Granidine does not seem to change the pharmacokinetic profile of Esomeprazole. Co-administration of Esomeparzole, Clarithromycin, and Amoxycillin has resulted in increase in the plasma levels of Esomeprazole and 14-hydroxclarithromycin. 

Store in a cool and dry place and keep away from light.


Asector® 20 capsule:  Each box contains 5 Alu-alu blister strips of 6 capsules each.

Asector® 20 tablet:  Each box contains 5 Alu-alu blister strips of 6 tablets each.

Asector® 40 capsule:  Each box contains 5 Alu-alu blister strips of 6 tablets each.